〒567-0085
大阪府茨木市彩都あさぎ7-6-8
TEL:072-641-9012(内線2402)
MAIL:moka@nibiohn.go.jp

English Page

研究業績

原著論文

Oka M. and Yoneda Y. Importin α: functions as a nuclear transport factor and beyond, Proceedings of the Japan Academy, Series B, 94: 259-274 (2018)

Miyamoto Y., Whiley P.A.F, Goh H., Wong C., Higgins G., Tachibana T., McMenamin P., Mayne L., Loveland K.L The Stk35 locus contributes to normal gametogenesis and encodes a lncRNA responsive to oxidative stress. Biol Open, 7: bio032631 (2018)

Tanaka T., Kasahara Y., Miyamoto Y., Takumi O., Kasai T., Onodera K., Kuwahara M., Oka M., Yoneda Y., Obika S. Development of oligonucleotide-based antagonists of Ebola virus protein 24 inhibiting its interaction with karyopherin α1. Org. Biomol. Chem., 16: 4456-4463 (2018)

Higa M., Oka M., Fujihara Y., Masuda K., Yoneda Y. Kishimoto T. Regulation of inflammatory responses by dynamic subcellular localization of RNA-binding protein Arid5a. PNAS, 115: E1214-E1220 (2018)

Miyamoto Y., Yoneda Y., Oka M. Protein Transport Between the Nucleus and Cytoplasm, Nuclear Architecture and Dynamics, Academic press, Chapter 17: 387-403 (2018)

Moriyama T., Tanaka S., Nakayama Y., Fukumoto M., Tsujimura K., Yamada K., Bamba T., Yoneda Y., Fukusaki E., Oka M. Two isoforms of TALDO1 generated by alternative translational initiation show differential nucleocytoplasmic distribution to regulate the global metabolic network. Sci. Rep., 6: 34648 (2016)

Miyamoto Y., Yamada K., Yoneda Y. Importin α: a key molecule in nuclear transport and non-transport functions. J. Biochem., 160: 69-75 (2016)

Miyamoto Y., Oka M. Data on dimer formation between importin α subtypes. Data Brief, 7: 1248-1253 (2016)

Yamada K., Miyamoto Y., Tsujii A., Moriyama Y., Ikuno Y., Shiromizu T., Serada S., Fujimoto M., Tomonaga T., Naka T., Yoneda Y. Oka M. Cell surface localization of importin α1/KPNA2 affects cancer cell proliferation by regulating FGF1 signalling. Sci. Rep., 6: 231410 (2016)

Oka M., Mura S., Yamada K., Sangel P., Hirata S., Maehara K., Kawakami K., Tachibana T., Ohkawa Y., Kimura H., Yoneda Y. Chromatin-prebound Crm1 recruits Nup98-HoxA9 fusion to induce aberrant expression of Hox cluster genes. eLIFE, 5: e09540 (2016)

Tsujii A., Miyamoto Y., Moriyama T., Tsuchiya T., Obuse C., Mizuguchi K., Oka M., Yoneda Y. Retinoblastoma Binding Protein 4-Regulated Classical Nuclear Transport Is Involved in Cellular Senescence. J. Biol. Chem., 290: 29375–29388 (2015)

Kimoto C., Moriyama T., Tsujii A., Igarashi Y., Obuse C., Miyamoto Y., Oka M. and Yoneda Y. Functional characterization of importin α8 as a classical nuclear localization signal receptor. Biochim. Biophys. Acta - Molecular Cell Research, 1853: 2676-2683 (2015)

Moriyama T., Percival A. P., Yamaguchi D., Obuse C., Miyamoto Y., Oka M., Yoneda Y. Identification and characterization of a nuclear localization signal of TRIM28 that overlaps with the HP1 Box. Biochem. Biophys. Res. Commun., 462: 201–207 (2015)

Sangel P., Oka M. and Yoneda Y. The role of importin-βs in the maintenance and lineage commitment of mouse embryonic stem cells. FEBS Open Bio, 4: 112-120 (2014)

Oka M., Moriyama T., Asally M., Kawakami K. and Yoneda Y. Differential role for transcription factor Oct4 nucleocytoplasmic dynamics in somatic cell reprogramming and self-renewal of embryonic stem cells. J. Biol. Chem., 288: 15085-15097 (2013)

Yasuhara N., Yamagishi R., Arai Y., Mehmood R., Kimoto C., Fujita T., Touma K., Kaneko K., Kamikawa Y., Moriyama Y., Yanagida T., Kaneko H. and Yoneda Y. Importin alpha subtypes determine differential transcription factor localization in embryonic stem cells maintenance. Dev. Cell, 26: 123-135 (2013)

Mizuguchi-Hata C., Ogawa Y., Oka M. and Yoneda Y. Quantitative regulation of nuclear pore complex components by O-GlcNAcylation. Biochim. Biophys. Acta -Molecular Cell Research, 1833: 2682-2689 (2013)

Tanaka S., Nakano K., Sekimoto T., Oka M. and Yoneda Y. Cell density-dependent nuclear accumulation of ELK3 is involved in suppression of PAI-1 expression.Cell Struct. Funct. 38: 145-154 (2013)

Oka M., Moriyama T., Asally M., Kawakami K. and Yoneda Y. Differential role for transcription factor Oct4 nucleocytoplasmic dynamics in somatic cell reprogramming and self-renewal of embryonic stem cells. J. Biol. Chem., 288: 15085-15097 (2013)

Nagai M. and Yoneda Y. Downregulation of the small GTPase Ras-related nuclear protein accelerates cellular ageing. Biochim. Biophys. Acta -General Subjects, 1830: 2813-2819 (2012)

Miyamoto Y., Loveland K.L. and Yoneda Y. Nuclear importin α and its physiological importance. Commun. Integr. Biol., 5: 220-222 (2012)

Ogawa Y., Miyamoto Y., Oka M. and Yoneda Y. The interaction between importin-α and Nup153 promotes importin-α/β-mediated nuclear import. Traffic, 13: 934-946 (2012)

Yasuda Y., Miyamoto Y., Yamashiro T., Asally M., Masui A., Loveland K.L. and Yoneda Y. Nuclear retention of importin α coordinates cell fate through changes in gene expression. EMBO J., 31: 83-94 (2012)

Sekimoto T. and Yoneda Y. Intrinsic and extrinsic negative regulators of nuclear protein transport processes. Genes Cells, 17: 525-35 (2012)

日本語総説

盛山哲嗣、岡 正啓「核ー細胞質間輸送」生体の科学 第66卷 第5号、p488-489 (2015)

宮本洋一、盛山哲嗣「インポーティンαファミリーと高次生命機能」生化学 第87巻 第1号、p16-21 (2015)

辻井聡、 岡正啓「老化と核-細胞質間輸送制御」生化学 第87巻 第1号、 p22-26 (2015)

宮本洋一「創薬ターゲットとしての核-細胞質間物質輸送」バイオサイエンス&インダストリー 第73卷 第4号、p288-291 (2015)

ページのトップへ